Sleep Bruxism is a condition that is receiving a tremendous amount of attention of late in the news. Perhaps as a result of the number of dentists who are providing high level diagnostics using a medical grade sleep bruxism monitor to collect surface EMG data. This kind of objective data has opened the opportunity to improve speed to treat for patient with jaw symptoms. Patients who clench and grind do not all generate pain or present with a jaw pain complaint in fact they may be unaware that they suffer from sleep bruxism. Often this underlying disease is associated with sleep disordered breathing and should be objectively evaluated and measured to better evaluate the severity of the condition and to rule out obstructive sleep apnea and related sleep disordered breathing.-ed BRUXISM THERAPY AND OBSTRUCTIVE SLEEP APNEA THERAPY FOR EVERY DENTAL PRACTICE Suzanne Haley DMD as previously presented on SleepScholar.com website January 20, 2016 Bruxism is a condition in which a person grinds or clenches his teeth. People who have bruxism may unconsciously or consciously clench their teeth together during the day or clench and grind them at night. Signs and symptoms of bruxism may include: sounds of grinding or clenching; teeth that are flat, fractured, or chipped; teeth that have abfractions present; increased tooth sensitivity; jaw or facial pain; tight and sore facial muscles; sore jaws; headaches; periodontal tissue damage; and indentations on the tongue. The cause of bruxism is unknown but is linked to such factors as stress, anxiety, fatigue, snoring, and sleep apnea. People who clench or grind their teeth during sleep are more likely to have some degree of apnea present. Obstructive sleep apnea (OSA) is the most common form of sleep apnea. Sleep apnea occurs when the muscles in the back of the throat fail to keep the airway open despite efforts to breathe. Sleep apnea is a medical condition in which breathing is briefly and repeatedly interrupted during sleep. An apnea occurs when the muscles fail to keep the airway open and there is a physical obstruction such as the tongue, pharyngeal muscles, epiglottis, and uvula that blocks the airway. This obstruction causes the patient to stop breathing during sleep. An apnea is an event where the patient stops breathing for a minimum of 10 seconds during sleep. A hypopnea is an event where the patient has significantly reduced airflow because of a partially blocked airway for at least 10 seconds while sleeping. Patients with obstructive sleep apnea will have multiple apneas/hypopneas every night while they sleep, with the potential to severely impact their health. There are three different types of obstructive sleep apnea. These classifications depend on the number of apneas and hypopneas, divided by the number of drops in oxygen saturation. OSA deprives the body of oxygen and untreated is a potentially deadly sleep disorder. OSA can increase an individual’s risk for a heart attack, stroke, hypertension, and cardiac disease. Dentists have a unique position and can play a major role in their patient’s health because many patients are seen several times in a year. As dentists we have familiarity and access to the oral cavity, airway, and neck. As dentists we examine and focus on the head and neck of our patients. We can view the patient’s airway, soft tissue, and dentition. We observe the tongue size, tongue shape, soft palate area, the patient’s neck size, periodontium, and the wear on the patient’s dentition. In the dental office, bruxism is seen in one out of every three patients. Two out of every five of these patients has undiagnosed or untreated obstructive sleep apnea. It is important to realize that patients who demonstrate bruxism often have obstructive sleep apnea. Sleep bruxism is considered a sleep related movement disorder. People who clench or grind their teeth during sleep are more likely to have other sleep disorders, such as snoring, pauses in breathing, and sleep apnea. Mild bruxism may not need to be treated. However, in some patients, bruxism can be frequent and severe enough to cause jaw disorders, damage to teeth, and headaches. Dentists can screen for teeth grinding and can tell if a patient is grinding their teeth at night. Bruxism can be treated with an appliance made to prevent grinding and /or clenching. Dentists can refer patients to their physicians for the diagnoses of sleep apnea and then dentists can treat sleep apnea patients with oral appliances as well. However, because there is a link seen between grinding and sleep apnea, dentists need to play a larger role and have a relationship with a sleep physician and other medical doctors. Dentists can diagnose and provide the therapy needed for bruxism and provide the therapy for obstructive sleep apnea, once a physician diagnoses the apnea which is a medical condition requiring a medical diagnosis. Dental sleep medicine is a fast growing area of dentistry. There are approximately 40 million people in the United States with obstructive sleep apnea (OSA), with 90% of those undiagnosed. One in four patients with OSA suffer from nighttime teeth grinding. The ending of an apneic event may be accompanied by a number of mouth phenomena, such as snoring, gasps, grunts, and mainly teeth grinding. Teeth grinding occurs because of the significant attempts to open the mouth to breathe. Bruxism usually occurs after an apnea event. One of the ways the brain tries to reopen the airway, in an unconscious state, is by grinding and clenching the teeth. Teeth grinding is a major indicator that you are struggling to keep your airway open at night and might suffer from obstructive sleep apnea. When the airway collapses, breathing becomes compromised. This is where you get snoring, which is just the sound that’s made when air is getting forced through a partially obstructed airway. Once the brain senses that breathing is dangerously compromised, it exits the deepest stage of sleep to regain control of the jaw muscles and reopen the airway – to keep a person breathing and alive. These sleep apnea cycles can occur from five to up to 70 times per hour during sleep. These events prevent one from entering the deepest stages of sleep where the brain and body tissues can repair themselves from the wear and tear of the day. A dentist’s role in this process is to provide screening, therapy for bruxism, and therapy for obstructive sleep apnea when diagnosed. Dentists are not only qualified to provide the necessary dental treatment for this life threatening disorder but are uniquely in a position to screen and refer our own patients for sleep apnea diagnosis. Another screening application the dentist can provide is the Epworth Sleepiness Scale (ESS) to all patients. ESS is a scale, which measures a person’s average level of daytime sleepiness.The scale consists of eight different routine life situations. Each question is rated from zero to three, with three having the highest chance of falling asleep. If a patient scores nine or above and demonstrates excessive daytime sleepiness this needs to be discussed and researched further for explanation on why the patient is excessively sleepy. When it is determined that a patient is a grinder/clencher, snores, and has an ESS score of 9 or above, the patient is a prime candidate for a sleep test. Patients may be referred to a sleep physician, pulmonologists, or their personal primary physician for a sleep study. The home bruxism/sleep test (STATDDS Bruxism/Sleep Monitor) is typically used to diagnose bruxism and sleep apnea (Figure 1). In the dental office, dentists can administer a home test to measure the patient for bruxism and at the same time receive the apnea/hypopnea index which measures obstructive sleep apnea. The AHI can be shared with the patient’s physician. The dentist can work with the patient’s physician as coprimary healthcare providers and come up with a treatment plan together that can address the bruxism and the obstructive sleep apnea. As dentists, we only diagnose the activities occurring during sleep that are related to the clenching and grinding. Heightened bruxism events occur more frequently at the end of an apneic episode. The results of the bruxism/sleep study are sent to a certified sleep physician who gathers the information and provides a diagnosis determined by the total number of pauses that occur per hour of sleep. If the patient has only grinding/clenching issues and no apneic events or drops in the oxygen saturation then a night guard is treatment planned for the patient. Dentists should not be fabricating and placing dental appliances without objective data from a bruxism/sleep test and a proper diagnosis, to avoid creating an obstruction in the patient’s airway with the appliance for grinding/clenching (Figures 2 and 3). Moreover, if the study is returned with a diagnosis of mild or moderate obstructive sleep apnea, then a proper dental sleep appliance should be one of the recommendations for treatment. A mandibular advancement sleep appliance can be fabricated for that patient and can be titrated based on post testing with the home bruxism/sleep monitor. There are several types of sleep appliances for the treatment of obstructive sleep apnea (Figures 4 and 5). The devices move the mandible and tongue forward allowing the airway to remain opened. There are appliances for a patient who is a bruxer and an OSA patient. There are oral appliances for an OSA only patient. Also, for severe sleep apnea sometimes a patient will wear a combination of an appliance with positive airway pressure therapy. Furthermore, for severe OSA who cannot tolerate a CPAP type device, an oral appliance is recommended as it is better for the patient to have some means of opening the airway and alleviating obstructive sleep apnea. Oral devices to treat obstructive sleep apnea must be prescribed by a physician and fabricated and fitted by a dentist. Dental oral appliances are convenient form of sleep apnea treatment. The compliance rate is higher than CPAP treatment with OSA patients. The devices offer the benefits of a significant reduction in apnea for mild to moderate OSA patients. Also, the elimination and or reduction in both grinding, clenching and snoring. Dental practices have the unique advantage of seeing their patients frequently and access to the oral cavity to identify potential sleep apnea patients.
One inescapable conclusion one would have to make about OSA therapy is that CPAP has dominated the scene for over 30 years. The current DME climate has reimbursement so low that it is difficult to get CPAP supplies locally in many areas. Often internet suppliers are the only option. CMS has changed its billing practices many times in the last 3 years resulting in consolidation of care providers and has really begun to affect compliance rates with CPAP. Dr Colin Sullivan the inventor of CPAP had this to say in an interview with the National Sleep Foundation entitled Past Present and Future of CPAP “Nasal CPAP use is now so common that I have to make myself go back to the beginning to answer this question. At the time of the first experiment, nasal CPAP as a treatment looked like a useful rescue therapy to give us time to find a surgical cure. So, yes I must say that I am indeed surprised that nasal CPAP is now the front-line therapy for sleep apnea. I recall that in the early days,patients would use the treatment as it had such a dramatic effect on their daytime function – their personal feedback was the key to CPAP’s continuing acceptance. We now know sleep apnea can cause all of the common vascular diseases, so we are asking people with less severe symptoms to use CPAP to prevent having a heart attack or stroke. However, the comfort of the systems has improved. I often ask my patients to think of CPAP like reading glasses. They are a nuisance but you can’t do without them. Unlike other therapies, they don’t have to worry about drug side effects.” It is often reported that CPAP compliance rates have dropped significantly in mild to moderate sleep apnea patients. The use of oral appliances for this subsection of diagnosed patients makes all the difference in compliance. Often combination therapy is a good choice for patients with sleep apnea and who have an active lifestyle or simply have a very high pressure on their CPAP. Gergens Orthodontic Lab reports a change in reimbursement by CMS that seems to indicate that Oral Appliance Therapy (OAT) has achieved the first line therapy status with Medicare. Read the article below and let me know what you think.-ed CMS Bets on Oral Appliance Therapy a blog post Gergensortho.com A running discussion for the last 6 years here at Gergens Orthodontic Lab has been the CPAP as Gold standard of sleep therapy vs Oral Appliance therapy debate. These discussions usually go for hours and have gone on for years. The strongest debate has been between David Gergen President of Gergens Orthodontic Lab and executive director of American Sleep and Breathing Academy (ASBA) and Randy Clare from ASBA. Back and forth compliance vs treatment efficacy. David Gergen has been back and forth to Washington working with congressman Marty Russo trying to get some traction within the federal government on this issue. The key point of distinction of course is what drives medical care in the United States is reimbursement. The story for CPAP in the reimbursment arena since competitive bidding became an issue has slowly restricted access to care and fed a consolidation of providers. Fewer providers to provide care and the care they can afford to provide is less personal which results in lower compliance rates which results in lower reimbursement. January 1 2016 CMS cut CPAP reimbursement by 25%. Will this affect a diagnosed OSA patients ability to get great care of course it will. On the other side of the ledger Oral Appliance therapy has not been a focus for CMS. The OAT program has been way underfunded. This has made access to oral devices for sleep apnea difficult for medicare patients. Dentists were not finding it easy to provide care for these patients because reimbursement was so low. January 1 2016 CMS raised reimbursement for OAT to $3700 in jurisdiction B (see attached EOB) If you don’t know your jurisdiction for medicare I have also added a map for your use. I expect that this will increase access to care significantly. I feel it indicates a trend and perhaps insurers are ready to consider higher compliance rates and better return on sleep therapy dollars. After all the dental team sees the patient at minimum every six months which is a much better way to manage a lifelong condition with severe health implications.
The practice of sleep treatment has come to rely on a number of different disciplines to contribute to the treatment of a patient with sleep disordered breathing. The dental community has made great strides as part of the effort to manage this life long disorder. Dr Louis Malcmacher and Dr Slocum in the case presentation below make an excellent case that often the dental team doesn’t know that the practice can provide sleep therapy. In the case below the link between facial aesthetics and migraine is made however the link between sleep bruxism, sleep disordered breathing and migraine can also be made. The use a medical grade sleep bruxism monitor to draw the conditions together objectively is interesting and should not be left out of the equation. Imagine if key staff members don’t understand how the dentist addresses these conditions how could a patient make the link. Please take a few minutes to read Dr Malcmacher’s presentation. Let me know what you think – ed Does Your Team Know What You Do? Article by Louis Malcmacher, DDS, MAGD previously appeared in Chairside dental Magazine Vol. 10-4 Oftentimes we as treating clinicians can suffer from a little bit of tunnel vision. A patient may come in for elective esthetic treatment, and we get so focused on that, we fail to see the broader picture. It is important to remember that every dental case has both esthetic and therapeutic components that must be blended together. This is especially true of facial esthetic treatment cases, as they relate directly to patients’ orofacial and temporomandibular joint (TMJ) conditions. Here is a case report from one of our American Academy of Facial Esthetics (AAFE) faculty members, Dr. Elizabeth Slocum, who is an outstanding dental clinician and educator with a practice in Cartersville, Georgia. This case is a prime example of blending the best esthetic and therapeutic outcomes possible for our patients. The other lesson to be learned from this case presentation is to ensure that your team knows all of the treatments that you, the dentist, are competent in and able to deliver to patients. I present Dr. Slocum in her own words: Andrea has worked with us for eight years now. She is as beautiful on the inside as she is on the outside. She was excited when I decided to take a course on BOTOX® (Allergan, Inc.; Irvine, Calif.) and dermal fillers with the AAFE. Since completing the course, I have treated her for dentofacial esthetics, and she loves the results. Through a series of events involving Andrea, I learned a valuable lesson about why it is important to make known all of the techniques and treatments that I’ve been trained to provide; a lesson that is doubly important in light of all that I’ve learned from the AAFE, as my employees, like yours, might not realize that dentists are capable of treating patients for facial esthetics, TMJ pain, orofacial and myofascial pain, and headaches and migraines. Andrea went home from work early one day not feeling well. She missed the next day too. She came back to work the third day still under the weather. As we spoke, I realized that she had been absent due to a migraine. I was a little shocked that she hadn’t thought of having me treat her migraine in conjunction with the facial esthetics treatment I had already been providing her. She agreed to treatment, and I made some adjustments that would account for her migraine. I treated her glabellar area, frontalis and crow’s feet areas, as well as her masseter and temporalis muscles. I used Xeomin® (Merz Pharma GmbH & Co. KGaA; Frankfurt, Germany) – available from STATDDS for dentists – a botulinum toxin just like and as effective as BOTOX that is more cost-effective and has been reported to have a faster treatment response. She never looked back. In fact, we still treat her for both facial esthetics and her migraines (which are now under control) on a regular schedule. Figures 1–4 show the before and after of the procedure. Figure 2: Patient after treatment, a blend of facial esthetics and elimination of her migraines and orofacial pain. Notice the reduction in masseter size, resulting in a more esthetic jawline. Figure 3: Patient before treatment showing muscle contraction that contributes to her migraine and orofacial pain. Figure 4: Patient after treatment showing elimination of dynamic wrinkles as a result of frontalis muscle relaxation and pain relief. Again, the lesson here is to share all of the procedures that you do with all of your employees. Every time you learn new material, share it with your entire team. I thought I had shared most of what I had learned, but I had really only talked with them about facial esthetics and TMJ pain – not nearly as much about headaches or migraines. We started doing “lunch and learns” by watching some of the video series available from the AAFE. The staff enjoys them, and it opens the door for them to ask questions about any of the procedures that we offer. They really want to know what we do and how to share the information when speaking to patients. Everything we learn and bring back to the office is basically an unknown to our team members, unless they go to the training with you – which is now something I do routinely. Think back to the first AAFE BOTOX, fillers, TMJ/orofacial pain, or trigger-point therapy live-patient training course you attended or video you watched – or any dental continuing education course for that matter. There’s so much information out there that clinicians can learn. We bring back new and exciting procedures and have all of that information in our heads or on a handout, but your team members will only learn what you share with them. Today, the AAFE uses the STATDDS® Bruxism and Sleep Monitor (STATDDS; Cleveland, Ohio) to establish a baseline bruxism-episodes index number as part of the patient’s initial diagnostics in order to better evaluate and treatment plan bruxism, TMJ pain and orofacial pain cases (Fig. 5). This monitor will also tell us whether or not the patient will have sleep disorders that might be a co-morbid condition or can be the cause of TMJ and orofacial pain. The results of the STATDDS Bruxism and Sleep Monitor will directly guide the dental clinician as to which bruxism appliance or oral appliance for dental sleep medicine is the best choice for each individual patient (Figs. 6–11). This article’s two main points are these: First, make sure your team knows all of the services that you are trained to provide. It is time for every dental practitioner to take his or her team along to continuing education, especially when introducing new services to the practice. Second, let’s start obtaining objective data on bruxism, which affects one out of every three patients. I will measure most patients first with a STATDDS Bruxism and Sleep Monitor test and then let the data drive the treatment plan. This is especially helpful in choosing appliances and deciding the correct muscle treatment. Education – especially live-patient training – is absolutely essential in the areas of bruxism, restorative dentistry, orofacial pain, dental and facial esthetics, dental sleep medicine, and oral appliances. The continued education of clinicians is important so we can ensure favorable long-term restorative prognoses for patients across the span of our careers. Successful restorative, bruxism, and orofacial pain treatment has now entered a new era with the use of cost-effective qualitative objective testing, botulinum toxin, and the known relationship of bruxism and OSA. The AAFE (www.facialesthetics.org) offers comprehensive live-patient training in the areas of botulinum toxin, dermal fillers, frontline TMJ/orofacial pain, dental implants, and bruxism/sleep therapy. Get trained today! Dr. Malcmacher is a practicing general dentist and an internationally known lecturer and author. He can be reached at 800-952-0521 or via email atdrlouis@facialesthetics.org. Disclosure: Dr. Malcmacher is president of the American Academy of Facial Esthetics (AAFE) and is a consultant for STATDDS. Visit www.facialesthetics.org for information about live-patient frontline TMJ/orofacial pain training, dental implant training, frontline dental sleep medicine, bruxism therapy and medical insurance, and BOTOX and dermal fillers live-patient training. You can also download Dr. Malcmacher’s resource list and sign up for a free monthly e-newsletter at the site.
Ribbon cutting ArrowHead Sleep Center Date: Tuesday January 26, 2016 Location: 10:00 am ArrowHead Health Centers Glendale, AZ Fundraiser: Time: 7PM until 10 PM Location: Padre Murphys Irish Pub, 4338 W Bell Rd, Glendale, AZ 85308 Sponsors: ArrowHead Pro Sleep, Gergens Orthodontic, Koala Sleep Centers, Redirect Health, ZQuiet, Budweiser, American Sleep and Breathing Academy CHARITIES: Phoenix Police Foundation and 100 Club of Arizona Public Safety Officers Speakers: Az Attorney General, Mark Brnovich (pronounced “Burn-O-Vich”) Alberto Gutier, Director of Arizona Governor’s Office of Highway Safety (GOHS) Arrowhead Pro Sleep Grand Opening Flyer Sleep Apnea is a condition that affects the lives of professional athletes and fans alike. With serious co morbid conditions like diabetes, heart disease and obesity the impact of sleep apnea is serious and treatable. The Arizona Cardinals join with Arrowhead pro sleep and current and retired NFL stars Marcus Allen, Eric Dickerson, Mike Haynes , Larry Fitzgerald (a lot of other Super bowl hopeful Cardinals) and our very own Roy Green. Special guest for the event include Arizona AG Mark Brnovich, representatives from Homeland Security and the ATF ,The Police department of Phoenix and the Fire department of Phoenix. This exclusive public awareness event is sponsored by the Pro Players Health Alliance for sufferers’ of SLEEP APNEA . NFL players, both current and retired, are raising awareness of this this disease. “We are striving to make an awareness to the 18 million plus who are suffering from sleep apnea and do not know where to turn for help.” Said Dr. Rudi Ferrate from Arrowhead Pro Sleep Division. Snoring, Apnea and interrupted sleep are more than an annoyance, they can be life threating Illnesses that can lead to major heath concerns. NFL players have experienced the loss of family members and team members due to untreated obstructive sleep apnea and are speaking out nationwide, urging fans and players to seek diagnosis and treatment of their sleep conditions. Keynote speaker for the evening is Attorneys General Mark Brnovich. “Sleep apnea reduces life span 7-15 years. 90% who die in their sleep due to a heart attack, the root cause is sleep apnea. Without treatment, statistics reveal staggering facts: there is a two and a half times greater risk of stroke and 60% higher risk of cancer. We cannot be on our game when we are feeling tired and weak due to a lack of sleep. Thousands are untreated and it’s past time to bring this awareness to the forefront. It is for this purpose that Arrowhead Pro Sleep Division exists. Our Center is unconditionally dedicated to providing complete patient diagnosis and sleep therapy.
Obstructive sleep apnea is a a lifetime disorder that requires the clinical team to plan long term and treat the whole patient. The literature and more importantly medical insurance providers urge careful evaluation of temporomandibular joint as a part of oral appliance clinical work up. I read the following article by Dr. James Fricton, which was previously published in the CDA journal, and I really got excited about his approach. This comprehensive Patient focused program seems to be exactly what the sleep apnea dentistry world needs to continue to grow. We have added some diagnostic and thereapeutic protocols and started to move away from single treatment protocols with combination therapy etc. Over the last 6 years surface EMG and the calculation of Bruxism Episodes Index (BEI) has become much more routine in the evaluation of sleep disorders and jaw parafunction. In my opinion the management of sleep disorders is much more a disease state management program that the application of a specific therapy without the comprehensive individualized management plan. Dr Fricton makes the excellent point that Clinicians tend to see what they treat and treat what they see. Clinicians tend to see what they treat and treat what they see. Clinicians who see a stress etiology treat with stress management; surgeons who see a joint pathology treat with surgery; and dentists who see a dental etiology treat the teeth. As a result, treatment success is often compromised by limited approaches that address only part of the problem There are innovations in the field that have come along recently such as the Quick Splint which give the clinician a wonderful tool to increasing speed to treat considerations and at low cost. Please take the time to read over Dr Fricton’s article and let me know what you think.- ed Temporomandibular Disorders: A Human Systems Approach James Fricton, DDS, MS ABSTRACT The face and associated cranial,oral and dental structures are among the most complicated areas of the body, contributing to an array of common orofacial disorders that include temporomandibular disorders (TMD), orofacial pain disorders and orofacial sleep disorders. This paper presents a broad, inclusive approach to diagnosis and management of TMD that reflects both conceptual models of human systems in understanding chronic illnesses as well as systematic reviews of treatment for successful management. The face and associated cranial, oral and dental structures are among the most complicated areas of the body, contributing to an array of orofacial disorders, including temporomandibular disorders (TMD), orofacial pain disorders, orofacial sleep disorders, oral lesions, dental disorders and oromotor disorders. Orofacial pain disorders are the most common of these problems and can cause symptoms of orofacial pain, jaw dysfunction and chronic head and neck pain, with a collective estimated prevalence of at least 20 percent of the general population (TABLE 1).1-7 To complicate matters, oral and craniofacial structures have close associations with the functions of eating, communicating, seeing and hearing, and they form the basis for appearance, self-esteem and personal expression and, thus, can deeply affect an individual’s psychological and functional status.7 A national poll found that adults working full time miss work because of head and face pain more often than for any other site of pain.5 The high prevalence, personal impact and poor access to care for these problems have led to an expanded role for dentistry in providing solutions. However, because dentists focus most of their patient care on treatment of the dentition and related structures, it can be a challenge to understand the broader scope of diagnosis and management of these conditions. Treatment of TMD, like many pain conditions, is often singular and can vary according to the clinician’s favorite theory of etiology. Clinicians tend to see what they treat and treat what they see. Clinicians who see a stress etiology treat with stress management; surgeons who see a joint pathology treat with surgery; and dentists who see a dental etiology treat the teeth. As a result, treatment success is often compromised by limited approaches that address only part of the problem. This paper summarizes a broader, more inclusive philosophy in diagnosing and managing TMD that reflects both new conceptual models in understanding chronic illnesses as well as systematic reviews of therapeutic strategies for successful management of TMD. Human Systems Theory: A Comprehensive Model for Understanding Chronic Illness Humans are complex, multidimensional and dynamic and live within an ever- changing physical and social environment. Yet our traditional biomedical model is based on a scientific paradigm that is unidimensional, reductionist and in exible because it is based primarily on understanding the underlying pathophysiology. While distinct pathophysiological mechanisms occur in all chronic conditions, understanding the multitude of factors that play a role in the onset, perpetuation and progression of the illness is the key to successful management.8 Thus, traditional scientific protocols often fall short in providing an adequate framework for explaining, predicting and influencing chronic illness and its outcomes. Scientific and clinical communities have been searching for a more flexible, holistic and integrated model that describes the changes in human biology that can occur in response to the circumstances in our lives which contribute to the balance between health and illness. Human systems theory (HST) provides this framework.8 As originally stated by Aristotle in 300 BC, “The whole is greater than the sum of its parts.” HST stems from research in general systems theory and originated in ecology out of the need to explain the interrelatedness of organisms in ecosystems.8-10 While conventional biological theories view the subject as a single entity, HST views a person as a whole with an interrelationship between the subparts of his or her life. These subparts are not static but rather are dynamic, evolving and interrelated processes. The practical application of HST to patient care requires that we understand basic HST principles as they apply to the development and alleviation of illness. These include: ■ Seeing the whole patient through the eyes of the biopsychosocial medical model.8-10 ■ Understanding recursive feedback cycles using cybernetics.11,12 ■ Seeing the broad cumulative impact of small changes using chaos theory.13-15 ■ Understanding the power of positive action through positive psychology and behavioral medicine to enhance health as part of the treatment of illness.16-19 These concepts provide a new model for understanding TMD and its management that is well founded in theory and science. It is beyond the scope of this paper to present an in-depth discussion of each concept. However, for those interested in reading further, the concepts are presented in a more creative format than traditional academic texts — i.e., as a murder mystery novel — as well as part of a University of Minnesota massive open online course (MOOC) at coursera.org/course/chronicpain. 20 The biopsychosocial medical model was first proposed by Engel in 1977 and suggested that to understand health and illness, one needed to look at the whole person and not simply at physical pathophysiology.8-10 It recommended that we “see the big picture” of illness. Most studies of risk factors and protective factors suggest that each person has a unique set of interrelated factors that can either perpetuate or protect from an illness, including TMD. These contributing factors correspond to each realm of our lives, including the mind, body, emotions, spirituality, lifestyle, social relationships and the physical environment (FIGURE 1). By improving them, the strategies for management have greater success than the sum of any individual treatment directed at one realm. Cybernetics, a concept defined in physics, was first applied to human systems by Bateson in 1978.11,12 It suggests that “what goes around comes around” and each element of a system generates a change, which causes feedback to the entire system. Positive feedback triggers a continuation of the cycle, while negative feedback leads to its discontinuation. This is often referred to as a self-reflexive or “circular causation” relationship. Positive and negative feedback cycles play an important role in sustaining a person’s illness over time (FIGURE 2). Patients with an illness often fall into the recursive cycles that perpetuate the illness. Contributing factors to an illness, such as repetitive strain, depression or poor sleep, are elements that sustain the cycle. Several types of change can influence these cycles (FIGURE 3). First-order change is based on “reinforcement” of existing elements that promote maintenance or escalation of the existing cycle and its related illness. A second-order change involves a “revelation” that makes a significant change from within the system through multimodal education, training and treatment that lead to a new state. This change may either be toward improved health or escalation of the illness, depending on the direction of change in the element. Finally, a third-order change is based on “enlightenment,” which produces a change from outside to achieve a new level of existence distinctly different from the original structure. Second- or third- order changes are the basis for significant improvement of a condition to create a new paradigm for the health of the individual. Small first-order compensatory changes made by a patient in response to TMD pain, such as reducing use of the jaw, taking an analgesic or other self care, can improve the illness if it is an acute self-limiting problem, at least in the short term. However, these compensatory changes may also allow a more complex illness to fall into a long-term chronic cycle (FIGURE 2). If a clinician can help a patient make higher order changes by understanding the multiple elements in the cycle and changing those keystone factors that perpetuate it, the illness may change more readily. Integrative care strategies that encourage second- order change within an existing cycle include splints, physical therapy and behavioral management of oral habits, sleep and muscle tension. This strategy works quite well for simple to moderate cases, but more complex patients may need a more robust intervention. In those cases, transformative care strategies encourage third-order changes that can lead to the most dramatic long-term results. Third-order change involves not only treatment of the TMD pain as noted, but also working with a team to identify all co morbid conditions and contributing factors and helping the patient make major changes to factors that may be perpetuating the long-term cycles. These changes could include managing a co morbid medical condition such as fibromyalgia, addressing stressful or abusive relationships and changing poor work situations. In this way, healthier, positive feedback cycles are set up that do not perpetuate the factors that drive the illness. Chaos theory was first popularized by Lorenz (1963) in a paper on the theories of diverse weather patterns entitled “Does the Flap of a Butterfly’s Wings in Brazil Set off a Tornado in Texas?” He presented evidence that small differences in initial conditions of a system might yield widely diverging outcomes within dynamic systems. Chaos theory suggests that “it’s the little things that matter the most.” When applied to health and disease, it suggests that multiple risk factors can each play a small role at early stages of a chronic illness. However, when these factors are combined, they will accelerate the condition dramatically. As FIGURE 4 illustrates, an illness begins with initiating factors such as acute physical injury of the muscles and joints. In most cases, this pain is transient and resolves without complication or persistence. However, if a sufficient number of contributing factors are present, even though small, the balance can shift from healing of acute pain to delayed recovery and chronic pain (FIGURE 2).44-50 Various underlying neural mechanisms, such as peripheral and central sensitization and wind-up, play a role in this process that is difficult to predict. Likewise, the presence of protective factors and early intervention in multiple factors will have the greatest impact in resolving the condition. Behavioral medicine, then, suggests that specific behavioral interventions such as exercise and oral habit reversal can help restore health and wellness. It complements theories on positive psychology that focus on building health, strength and positive virtues as much as on correcting illness, problems and vices.16,17 The Aristotelian idea that we are what we repeatedly do is supported by much research in achieving health and wellness. These theories explain the diverse results of placebo-controlled clinical trials for TMD pain and other pain conditions which suggest that many different interventions, from splints and medications to physical and cognitive-behavioral therapies and even injections and surgery, can all be used to alleviate TMD pain.21-39 The effect of each of these interventions beyond the placebo effect may be small, but they are all significant. Furthermore, by combining these concepts in a multimodal integrative model of care that is based on a human systems approach, the small effects of multiple interventions employed at the same time can result in the greatest positive outcomes. Thus, the evaluation and management approaches proposed in this paper follow these principles. Principles of Evaluation The principles of HST can be applied to the evaluation of patients with TMD by employing an inclusive problem list, determining the complexity of the case and following the decision tree for increasing the potential for successful management. Determine the Problem List. HST expands the traditional “problem list” to include both the physical diagnoses and the contributing factors in each realm. The physical diagnosis is the physical problem that is responsible for the chief complaint and associated symptoms. The orofacial pain disorders noted in T A B L E 1 are included in this definition of the scope of dental practice because they have characteristics that involve the oral cavity, maxillofacial area and/or the adjacent and associated structures. Contributing factors include those that initiate, perpetuate or result from the disorder but in some way complicate the problem. These risk and protective factors are diverse and involve the seven realms of our lives:40-63 the physical (physiologic, genetic, molecular); lifestyle (repetitive strain, posture, lifestyle, eating, sleep); emotional (depression, fear, anxiety, anger); social (relationships, abuse, secondary gain); cognitive (attitudes, understanding, honesty); spiritual (faith, beliefs, purpose); and environmental (accidents, pollution, disorganization, hygiene). Specific risk factors for chronic pain may include peripheral factors such as repetitive strain, oral and postural habits, central mediating factors such as anxiety and depression, and comorbid conditions such as fibromyalgia, somatization and catastrophizing. Protective factors reduce vulnerability to chronic pain. These factors, which include the level of coping, self-efficacy, patient beliefs (e.g., perceived control over pain, belief that pain is a sign of damage) and social support, can also affect outcomes. Determining Complexity. The level of care for patients can also vary considerably depending on whether their condition is simple or complex. Patients with complex TMD often present with a frustrating medical and dental situation, which may include persistent aggravation of pain, multiple clinicians, long-term medications, repeated health care visits and an ongoing dependency on the health care system. Successful management of these patients is enhanced if the level of complexity is determined and matched to the complexity of the treatment strategy. Singular treatment strategies such as self care, physical therapy or splints can be quite successful with simple patients who have few contributing factors, but these treatments often fail in complex patients because of the chronic nature of the disease, central sensitization and long-standing maladaptive behaviors, attitudes and lifestyles. Decision Tree for Triaging Patients. FIGURE 5 outlines the decision tree for sequencing evaluation and management of simple and complex cases. Matching the complexity of a patient with the complexity of the management strategy is the key to success. Once you develop the complete problem list, including contributing factors, it can provide criteria to distinguish simple and complex patients. Complexity of the patient increases with factors such as: ■ Presence of multiple comorbid conditions. ■ Persistent pain lasting longer than six months. ■ Significant emotional problems (depression, anxiety). ■ Frequent use of health care services or medication. ■ Daily oral parafunctional habits. ■ Significant lifestyle disturbances. In addition, some complex patients warrant deferral of treatment until more complex problems are addressed. The criteria for not treating until these problems are resolved include factors such as: ■ Patient has primary chemical dependency. ■ Patient has primary psychiatric disorder. ■ Patient is involved in signs cant litigation. ■ Patient is overwhelmed with other concerns. ■ Patient is not motivated. Once complexity is determined, the appropriate level of care that matches the complexity of the patient needs to be implemented (FIGURE 3). For example, a patient with acute self-limiting conditions can be managed with self-care strategy training from a health educator. TMD patients with multilevel problems require a second-order change that uses multimodal treatments as implemented by a single clinician. This integrative care strategy can include multiple treatments, such as splint, exercises, oral habit instruction, medication and palliative self care, to achieve second-order change with improvement over two to four months. Use of a Health Care Team. Complex patients who have major life issues require a third-order change implemented by an interdisciplinary team to achieve success. This transformative care strategy involves the team of clinicians, such as a dentist, physician, health psychologist and physical therapist, working together with the patient to achieve success.66-68 Different specialists can address different aspects of the problem in order to enhance the overall potential for success. Teams can be interdisciplinary (one setting) or multidisciplinary (multiple settings). A team approach helps in understanding and managing the whole patient, allows multiple aspects of the problem to be treated simultaneously, improves patient compliance and outcome, saves time and is more economical and more enjoyable because the team works together. To address every aspect of the problem, treatments may include cognitive-behavioral therapy, counseling, mindfulness meditation, physical medicine treatments, medications, splints, exercises with physical therapy, occlusal therapy and surgery. A consistent philosophy and message to the patient is needed, including the importance of self care, self responsibility and education using concepts of HST. Success depends on communication, integration among clinicians and proper patient selection. With complex patients, improvement, but rarely resolution, is typically achieved in six months. Interestingly, the economics of this model are quite favorable for each of the stakeholders, including the patient, the health care provider and the health plan. The patients receive more comprehensive effective care that is convenient if it is interdisciplinary in one setting. This not only has a higher potential to achieve success but also reduces the need for doctor shopping and single sequential trial-and-error treatments. Thus, the health plan’s long- term costs are reduced compared with a patient whose treatment continues to fail and who bounces from one doctor and intervention to another. Finally, the clinicians within a team practice benefit economically because more of them are providing care and generating income to cover the overhead of the practice. It’s a rare win-win-win scenario. Principles of Management Successful management of TMD is focused on treating the diagnosis and reducing the contributing factors in order to achieve the goals of: ■ Reducing or eliminating pain. ■ Restoring normal jaw function. ■ Restoring normal lifestyle functioning. ■ Reducing the need for future health care. Once complexity is determined, the management options for TMD in general are consistent with treatment of musculoskeletal disorders in other parts of the body. The treatments involve interventions that have been documented with randomized controlled trials and are within the scope of dental practice to deliver or recommend.21-39 They include both reversible and irreversible treatments. Reversible treatments designed to encourage healing in the muscle and joints include self care, behavioral therapy, splints, medications and physical medicine. Irreversible treatments include joint surgery and permanent occlusal treatments. To determine whether the problem is self-limiting, self care should be initiated first. If the problem does not resolve within a few weeks and there is evidence of progression and/or persistence, treatment can proceed if pain and/or locking is severe enough to affect functioning or quality of life and the patient desires treatment. Each type of treatment is discussed briefly. Reversible Treatments Self Care. A key determinant of successful management of any musculoskeletal disorder involves educating the patient about the disorder and the necessity of compliance with the self-care aspects of management, including exercise, habit change and proper use of the jaw (TABLE 2).30,31 Information about self care should be provided to all patients and in some cases is the only strategy needed. Behavioral Therapy. Approaches to changing maladaptive habits and behaviors should be addressed and presented as an integral part of the overall treatment program for all patients with TMD and poor oral habits.32,33 Behavior modi cation strategies are the most common techniques used to change habits. Although many simple habits will change when the patient is made aware of them, changing persistent habits requires a structured program facilitated by a clinician trained in behavioral strategies. Habit change using a habit reversal technique can be accomplished when the patient becomes more aware of the habit, learns how to correct it (i.e., what to do with the teeth and tongue) and knows why it is important to correct it. When this knowledge is combined with a commitment to conscientious monitoring, most habits will change. Progress in changing habits should be addressed at all appointments. In some cases, patients may have significant psychosocial problems that accompany a TMD and may bene t from medication or counseling by a mental health professional. Prior to initiating treatment, a decision should be made as to whether the psychological distress is the primary problem. If this is the case, treatment of the psychological problem is best accomplished first and as an issue separate and apart from the TMD. Intraoral Splints. Splint therapy can be effective alone or in combination with other treatments for each stage of temporomandibular joint (TMJ) internal derangements and myofascial pain.22 Although there are many useful types of splints, four are commonly used for TMD: the full-arch stabilization splint, the anterior repositioning splint, the anterior bite plane and the posterior bilateral partial coverage splint. Complications that can occur with the use of any splint include caries, gingival inflammation, mouth odors, speech difficulties and/or psychological dependence on the splint. The most serious complication is major irreversible changes in the occlusal scheme (open bites) that occur because of long- term use of partial coverage splints such as the anterior bite plane and the posterior coverage splint. Splints should not be designed to move teeth orthodontically during treatment of a TMD. Pharmacotherapy. The most commonly used medications for pain are classified as nonnarcotic analgesics (nonsteroidal anti-in ammatories), narcotic analgesics, muscle relaxants, tranquilizers (ataractics), sedatives and antidepressants.37-39 Analgesics are used to allay pain, muscle relaxants for muscle tension and nocturnal activity, tranquilizers for anxiety, fear and enhancing sleep and antidepressants for pain, depression and enhancing sleep. Opioid analgesics have their own problems because of the potential for abuse and should be used sparingly and only with patients who have intractable chronic pain, no psychiatric conditions and no history of chemical abuse. If prescribed, clinicians need to follow speci c opioid prescribing standards such as use of pain contracts, urine toxicology testing, suspension of medications with violation and other guidelines found at fsmb.org/pdf/2004_ grpol_Controlled_Substances.pdf. Despite the advantages of medications for pain disorders, problems can occur because of their misuse. For this reason, an important goal of treatment for most patients is to eliminate the need for medications long term. With chronic pain patients, termination of current medications should take precedence over prescribing additional ones. Problems that can occur from use of medications include chemical dependency, behavioral reinforcement of continuing pain, inhibition of endogenous pain relief mechanisms, side effects and adverse effects from the use of polypharmaceuticals. Physical Medicine. The use of physical medicine techniques follows the same orthopedic and physical therapy guidelines as the evaluation and treatment of any musculoskeletal condition.23 Many exercises and modalities are available to help reduce pain and tenderness and increase range of motion. Exercises are recommended to stretch, strengthen and relax muscles, to increase joint range of motion, to enhance muscle strength or to develop normal arthrokinematics. They are prescribed in order to achieve specific goals and are changed or modified as the patient progresses. Once the patient has reached the goals of the treatment, a maintenance level of exercise is recommended to assure long- term resolution of the patient’s problems. In some cases of structural joint problems, limited range of motion and inflammation, ultrasound, iontophoresis, phonophoresis, superficial heat, cryotherapy and massage have been found helpful. Electrotherapies such as electrogalvanic stimulation and transcutaneous electrical stimulation have also been shown to be useful. Muscle and joint injections may also be recommended. However, these modalities typically have short-term effects and need to be used with exercises to maintain the improvement. For this reason, they should be used only until there is no longer a change in objective signs and/or improvement in pain. Irreversible Treatments In most cases, TMD problems improve with self care in combination with reversible treatments that encourage the natural healing processes of the muscles and joints. Irreversible treatments involve risk and should be used only if specific criteria are met. This applies to both TMJ surgery and permanent dental stabilization. Surgery. TMJ surgery has become an effective treatment for structural TMJ disorders.34-36 However, the complexity of available techniques, the potential for complications, the frequency of behavioral and psychosocial contributing factors and the availability of nonsurgical approaches mandate that TMJ surgery be used only in selected cases that meet specific criteria. The decision to treat a patient surgically depends on the degree of pathology present within the joint, the success or failure of appropriate nonsurgical therapy and the extent of disability that the joint pathology creates. A discussion of individual techniques is beyond the scope of this paper and can be found in the current American Association of Oral and Maxillofacial Surgery (AAOMS) position paper on TMJ surgery. Surgical management may vary from the closed surgical procedure (arthroscopy) to an open surgical procedure (arthrotomy), depending on the degree of disk deformity and degenerative changes. Each of the following criteria, adapted from the AAOMS criteria, should be fulfilled before proceeding with TMJ surgery: ■ Documented TMJ internal derangement or other structural joint disorder with appropriate imaging. ■ Evidence suggesting that symptoms and objective findings are a result of disk derangement or other structural joint disorder. ■ Pain and/or dysfunction of such magnitude as to constitute a disability for the patient. ■ Prior unsuccessful treatment with a nonsurgical approach that includes a stabilization splint, physical therapy and behavioral therapy. ■ Prior management of bruxism, oral parafunctional habits and other medical or dental conditions or contributing factors that will affect surgical outcome. ■ Patient consent after a discussion of potential complications, goals, success rate, timing, postoperative management and alternative approaches, including no treatment. These conditions maximize the potential for a successful outcome but cannot guarantee it. Patients with factors such as bromyalgia, depression or resistant nocturnal bruxism present with a complexity that has a poor prognosis. In addition, a full knowledge of complications and the reasons for surgical failure can help clinicians make this decision. Once this information is available, a realistic discussion of the prognosis, the patient’s expectations and any complicating factors can help a patient make a correct decision about surgery. Postoperative physical and behavioral therapy should be integrated into the overall surgical management. Permanent Dental Stabilization. Permanent dental treatment may be needed for some patients to provide stable occlusal support and function for the dental and temporomandibular structures.40 These treatments include occlusal adjustment, restorative dentistry, fixed or removable prosthodontics and orthodontics with or without orthognathic surgery. If needed because of poor stability of the dentition, permanent treatment is recommended only after pain has been reduced and normal jaw function restored. The criteria for using secondary dental treatment to maintain comfort and function of the temporomandibular structures include: ■ The function and stability of the occlusion does not provide adequate orthopedic support. This may be due to missing teeth, skeletal malocclusion or gross interferences in dental function. ■ The lack of stable dental support is demonstrated to be directly related to aggravation or recurrence of the TMD after primary treatment of the disorder has been successfully completed. Permanent dental treatment should proceed with the most conservative approach that will provide adequate function and stability of the occlusion. This ranges from occlusal adjustments to restorative dentistry to improve the dental occlusion and orthodontics to orthognathic surgery for changing the position of the teeth and skeletal relationships. Conclusion TMDs are common problems that can cause orofacial pain, jaw dysfunction and chronic head and neck pain, with a collective estimated prevalence of at least 20 percent of the general population (TABLE 1).1-7 Because oral and craniofacial structures have close associations with functions of eating, communication, sight and hearing and form the basis for appearance, self-esteem and personal expression, they can deeply affect an individual’s psychological, behavioral and functional status.8 Thus, understanding TMD with a conceptual model that reflects a comprehensive and integrated problem list that is inclusive and flexible can better prepare clinicians to manage the full diversity of patients, from self limiting to simple to complex. 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Integrative Medicine and Systemic Outcomes Research. Issues in the Emergence of a New Model for Primary Health Care. Arch Intern Med 2002;162(2):133-140. 68. Mann D. Moving Toward Integrative Care: Rationales, Models, and Steps for Conventional-Care Providers. J Evid Based Complementary Altern Med October 2004 vol. 9 no. 3 155-172. 69. Fricton J, Hathaway K, Bromaghim C. The interdisciplinary pain clinic: outcome and characteristics of a long term outpatient evaluation and management system. J Craniomandib Disord, 1(2):115-122, 1987. THE AUTHOR, James Fricton, DDS, MS, can be reached at frict001@umn.edu. James Fricton, DDS, MS, has devoted his career to patient care and research in temporomandibular and orofacial pain disorders. He is a senior researcher at the HealthPartners Institute for Education and Research and treats patients at the Minnesota Head and Neck Pain Clinic in Minneapolis. He is professor emeritus in the Department of Diagnostic and Surgical Sciences in the School of Dentistry at the University of Minnesota. Dr. Fricton has published and lectured extensively, is the author of TMJ and Craniofacial Pain: Diagnosis and Management, Myofacial Pain and Fibromyalgia and Advances in Orofacial Pain and TMJ Disorders and is serving as president of the International Myopain Society. Conflict of Interest Disclosure: None reported. Republished from CDA JOURNAL, VOL 4 2 , Nº 8 AUGUST 2014
(Keith Thornton, Barry Glassman, John Viviano, Jason Tierney, Steve Carstensen, Dan Tache, Harry Ball, Kent Smith, Erin Elliott, Les Priemer, Daniel Klauer, Steve Lamberg, Dennis Marangos, Tony Soileau, Christopher Kelly, Shouresh Charkandeh) The LinkedIn Discussion Group, “SleepDisordersDentistry” has just completed an open discussion on “Anterior Discluding Stop Design, What, Why, When, How and Which… ”. Here is a consensus for all to ponder. What was asked, “Anterior Discluding Stop Design, some clinicians make only this design and some never make this design. What is it, Why use it, When should we use it, When should we not use it, How should it be designed and Which appliances lend themselves best to this Stop?” What was said, An Anterior Midpoint Stop (AMS) is by virtue of design inherent for certain oral appliances such as the TAP or Lamberg Sleep Well, and can be an option for others such as the Somnodent or Panthera. Keith Thornton’s summary of the rational for using the AMS concept for his TAP appliance provides insight as to benefits associated with the AMS design: Room for tongue laterally (freeway Space) Adjustment of Occlusion with Protrusion (Christianson’s Phenomenon) Single adjustment mechanism, both horizontally and vertically, easier for patients to adjust Adjustable while in mouth Wide lateral freedom of movement Can adjust past maximum protrusion to passive stretch Simple Mechanism Easy to Tripod or equilibrate on protrusion Maintains straight line protrusion Although Keith is discussing the TAP appliance, this list provides some meaningful rational for an AMS. Barry Glassman pointed out that the AMS design results in significantly less muscle activity. The literature supports this concept with EMG studies dating all the way back to Williamson and more recently Hatori (short arch). Barry stressed that AMS does not control the initiation of the centrally mediated parafunctional activity; it simply has the effect of reducing muscle activity and thus reducing the resulting forces imposed on the dentition with parafunction. Particularly important, since almost all of the untoward side effects associated with an OSA appliance are a result of forces fueled by muscle. When asked whether he ever uses posterior stops, Barry’s response was, “Many top notch dentists practicing sleep medicine routinely use posterior stops. Clearly they do not seem to have major untoward effects as a result — and when I use an Oasys, in a maxillary edentulous case, with posterior stops, we do not routinely run into problems as a result. It is interesting to discuss this with Steve Bender, a dear friend who understands anterior midpoint stop theory and was a co-author of a survey we published on over 75,000 uses of anterior midpoint stops concerning their effectiveness and the untoward effects. Steve will tell you that he tends to use no posterior stops — until a patient demonstrates some discomfort — and then he adds them. What is happening here, I would propose, is that the particular force vectors, in combination with the patient’s component adaptive capacity, needed to be altered. I am suggesting that the way to minimize this potential, is to decrease the force vectors MAGNITUDE, and to improve the likelihood of the joints not being involved (despite the inaccurate theories proposed that anterior component crush joints), is to use anterior stops from the start. This also, by the way, makes titration much simpler, and allows patient titration without concerns of altered posterior force vectors creating problems.” Actually, Barry’s approach seems to jive closely with Keith’s post. Of course, by nature of the design of his appliance, Keith starts with AMS on everyone (citing similar reasons to Barry) then adds posterior stops in a small subset of patients when there are problems. Barry feels that adding these posterior stops changes up the force vectors (quantum, direction for example), bringing them within the patient’s adaptive capacity to tolerate them. The survey of over 75,000 uses of AMS Barry mentioned was on non-OSA appliances and documented efficacy and untoward effects. Admittedly, a survey, and not a RCT, but considering the number of cases, this review of AMS use provides valuable insights. In terms of non-sleep appliances, those who don’t use AMS reported higher levels of occlusal changes as opposed to those who do. Barry pointed out that using AMS concepts in sleep appliances does not create the same forces/mechanisms as it does in the use of parafunctional control only and that with any appliance therapy, informed consent and appropriate risk benefit decision-making is critical. This paper can be found at the following LINK: https://www.dentalaegis.com/id/2011/12/patterns-of-use-for-an-enhanced-nociceptive-trigeminal-inhibitory-splint Steve Carstensen posed an interesting question, “Since the mandible is already postured forward and open, thus decreasing the mechanical advantage of the closing muscles, I wonder how much difference there would be between that as a ‘start’ position and any movement further forward or open or laterally from there.” Barry’s response, “I don’t know of any well done study that evaluated EMG activity with and without AMS when the mandible is advanced…I am not aware of any evidence suggesting a decreased mechanical advantage with anterior repositioning…What I can tell you is that we have put EMG’s on patients with sleep appliances and proceeded with maximum voluntary clenches with AMS and without and seen the same 75 percent reduction in the Anterior Temporalis and 50 percent reduction in the Masseter. Note: This was not a controlled study, and done in our office — many times. Now what I never did was compare the EMG potential with natural dentition vs. with the advanced mandible.” Personally, I have experienced issues with the lower appliance fracturing under the anterior discluding ramp, and also, on occasion, patient’s complaining about pain on the lower anterior teeth below the anterior discluding ramp, which disappeared when I added posterior support. When I asked Barry about this, he felt that perhaps it was a design problem. Tips from Barry about anterior discluding ramp design: Width should be approximately the width of the central incisors Long axis of discluding ramp should coincide with long axis of mandibular incisors, such that forces run along the long axis of the lower dentition Ensure that the ramp cannot slide off the lower appliance as the mandible is advanced or retruded (Keith Thornton, Barry Glassman, John Viviano, Jason Tierney, Steve Carstensen) However, not every clinician is a fan of AMS, one stated “trying to reduce force by the use of a stop is counter intuitive”. Others expressed concern about the AMS restricting the tongue from moving forward and out of the airway, increasing vertical more than desired and mandibular anterior tooth discomfort caused by clenching forces. Some clinicians stated that appliances with occlusal rims were more comfortable, ensuring less torque on the anterior teeth and a better distribution of forces. Adding AMS to the initial appliance design was discussed for patients presenting with a history of bruxism or taking medications that are associated with an increase in bruxism, or having chronic pain or a movement disorder. Adding AMS after the fact to an existing appliance was also discussed for patients experiencing repeated fracture (eg. Dorsal design). As a cautionary note, it was also mentioned that patients with degenerative joint disease would benefit from posterior support as a protective measure for the TMJ. Concern was expressed regarding the anterior open bite issue associated with the NTI appliance. However, since OSA appliances do not limit their tooth contact to the anterior teeth, there is no reason to believe that this would happen with an OSA appliance, nor did anyone report this occurring. My thoughts are that an NTI appliance leads to a decrease in muscle activity, but does not eliminate it. So, the propensity for occlusal changes have to do with whatever (parafunction) bruxism remains, the force vectors and the fact that these forces are concentrated on the anterior teeth that the appliance touches. However, with a full coverage design, an anterior discluding ramp would not result in the same concentration of forces on those anterior teeth and in fact distribute the forces over the teeth the acrylic is engaging. This is one of my concerns about the new discluding stop on the Panthera. Since the current appliance design does not touch the lower or upper anterior teeth. The forces are translated to the posterior teeth that the appliance engages (with a cantilevered effect). So, is this going to lead to more tooth movement? Something we will have to monitor. Regardless, once again, Panthera leads the way with innovation in the 3D printed nylon appliance department, with addition of the AMS design to their lineup. Kent Smith discussed that his primary concern is patient comfort, which he believes relates to adherence to therapy. Consequently, he prefers a minimal vertical opening, which is not congruent with AMS design. However, he does place one when dealing with a prior NTI patient. He likes the MicrO2 appliance due to its minimal vertical, and uses a 2mm George Gauge bite fork when taking the bite for this appliance in order to ensure a minimal vertical opening. However, he limits use of the MicrO2 to milder cases due to limited titratability. Steve Lamberg discussed the design features of the AMS on his Lamberg Sleep Well appliance, “When I decide to add posterior stops on the Lamberg Sleep Well (based on deprogrammer concept), I add a “jig” on the anterior of the lower member on what we call the “Protrusive Element’s Mate”. I make it 3 mm wide and 2 mm high. The purpose of this addition is to simplify maintaining the posterior stops in occlusion. As mandible is protruded, the posterior stops drop out of occlusion and with the anterior jig added to the protrusive element’s “Mate”, I can disk off .5mm (or whatever it takes) to bring the posterior stops back into occlusion. This is a bit quicker and easier than mixing and adding acrylic to the posterior stops each time you adjust the appliance.” Shouresh Charkhandeh uses AMS less than 10% of the time, his rational for use, Patients with sleep bruxism/ parafunction that cannot be controlled by treating OSA alone 2) Increasing vertical without the need to have a heavy rim of acrylic around the entire arch Using signs and symptoms as criteria, if Shouresh determines the possible need for AMS, he prescribes an acrylic appliance so that AMS can be added if necessary. When asked why he does not use it all the time up front, he responded, “ I personally like to have a full-balanced occlusion in my appliances if possible. That is always my first choice. I do use TENS as well in some of the cases and like the appliance to be made to that exact position I want the option of using appliances like Narval/Panthera Vertical Opening limitation – typically a more open vertical would be required for “ADR” and in some cases that could interfere with “lip competency”. Finally, Tony Soileau shared with us that he experienced occlusal changes when using AMS. However, since he added physiotherapy (deep tissue massage, acupressure, stretching, yoga, diaphragmatic breathing) to his regular protocol for all sleep patients, these issues seem to have reduced. The theory being that unhappy muscles are the “root” of the problem. Tony says, “Damage from years of clenching, poor posture, work environment, etc has the patients entire body in a knot. Once you start to “untangle” the knot, the posture, head position, bite, etc will change; easy to blame it on the appliance. We start with the muscle therapy the day we take the bite.” (Dan Tache, Harry Ball, John Viviano, Kent Smith, Erin Elliott, Les Priemer, Daniel Klauer, Steve Lamberg, Dennis Marangos, Tony Soileau, Christopher Kelly, Shouresh Charkandeh) In summary, there is literature evidence that AMS reduces muscular activity when using anterior midpoint stop appliances. However, to understand exactly how this applies to OSA appliances that cover the entire dentition and advance the mandible, we can only rely on anecdotal and case study evidence. Barry Glassman has evaluated this in “many” patients and has documented similar reduction in muscle activity. Consequently, AMS is his default design for OSA appliances, resorting to placement of posterior stops only when patients are having difficulties. His explanation as to what the posterior stops do, “the particular force vectors in combination with the patient’s component adaptive capacity needed to be altered”, with the intention of bringing them within the patient’s adaptive capacity. Of course, there are advantages to not having posterior contact, such as facilitating appliance advancement and providing lateral tongue space. However, there are those that prefer the stability of a full occlusal rim and feel that the anterior discluding ramp may interfere with where the tongue may want to be. Other factors deterring the exclusive use of AMS is the increase in vertical it requires and the inability to stabilize a jaw to a particular “TENS” determined posture. Finally, there is the concern of providing appropriate TMJ support for those with degenerative joint disease. Barry’s comment regarding this concern follows, “There is a common misunderstanding that without posterior stops, the loading will increase, this is based on a mechanical model that is not accurate and does not look at the force vectors created by the elevator muscles.” When asked, “When is it appropriate to use AMS on an OSA appliance? in typical “Barry Talk”, his response was “Only when you want less forces during parafunction, Just Sayn ;)” Some clinicians start off with AMS and add posterior stops in a subset of patients when necessary, yet other clinicians start off without AMS and add it in a subset of patients when necessary. Interestingly, these are top clinicians that are all taking very good care of their patients. Clearly, there is a need for some good studies here. Similar to many other aspects of Sleep Disorders Dentistry, we have different approaches resulting in good outcomes. Sharing these opinions and keeping an open mind can only make us better clinicians. Once again, I would like to express a heartfelt thanks to all that participated in this discussion. As always, these consensus articles should be considered working documents, meant to guide those clinicians beginning in this field and also present some valuable insights to those of us that have been at it a while. I look forward to future discussions on our SleepDisordersDentistry LinkedIn group!
High Risk Women Age 67 Poor compliance, unmonitored for 5 years Complaint and AHI within normal limits after 4 months with Sleep Treatment Specialists (STS) treatment Case Highlights Chief Complaints: OSA/EDS/Snoring Diagnosed severe OSA 2009 CPAP non compliant/failure Elevated BMI & HPTN Gastric bypass /Septaplasty STS treatment plan with OAD. PAP and positional therapy AHI dropped from 72-3.5 Indicates feeling well and rested Follow up visits Every 3 months Hx: Before Sleep Treatment Specialists Patient X had a sleep study done in 2009. Results showed she had severe obstructive sleep apnea, with an AHI of 72.5. She was prescribed a CPAP, with a set pressure of 14 cmH2O. Over the years she experienced significant complications with her CPAP use due to removal during sleep and insufficient seal. Her medical history includes OSA, TMJ, HPTN, arthritis, and breast CA. She has undergone multiple surgical procedures over the years including gastric bypass and Septoplasty. She was referred to Sleep Treatment Specialists by her PCP July 2014 by for excessive daytime time sleepiness, non CPAP compliant, elevated BMI, HPTN and TMJ. She was interested in a CPAP alternative. Sleep Treatment Specialists Plan & Treatment Initial New Patient Consult: 07/21/2014 For the first consult we obtained full history from the patient. Impressions were taken for an Oral Airway Device (OAD). We gave her a 5 day Auto set PAP trial. We also went over the importance of positional therapy and weight loss. 07/28/2014 Patient returned APAP. She really liked the auto set pressure and was able to tolerate it a lot better than her set pressure. Her set pressure was too high for her. We ordered her a new APAP machine. 08/18/2014 The Patient picked up her OADAfter making a few adjustments she did a home sleep test to measure the efficacy of her OAD her AHI dropped from 72 to 22! 12/17/2014 The patient brought her new CPAP in to be adjusted to her settings. She came in a few weeks later. She is compliant with combination OAD and CPAP Sleep Treatment Specialists Dr. Brad Eli is a nationally-recognized leader in sleep disorders treatment and pain management. His expertise in sleep led him to develop a patient-centered method that offers a variety of sleep treatment options and matches each patient with the best treatment for their symptoms and lifestyle. Patients diagnosed and treated by Dr. Eli consistently achieve better compliance rates and improved outcomes. Dr. Eli is the first Medicare and Tricare approved provider for multi therapy sleep treatment in Southern California. Dr. Eli earned a post doctoral Master’s Degree at UCLA where he received advanced training in sleep disorders. He remains the only expert with this unique skill set in the San Diego region. He is a member of numerous professional associations including the American Academy of Sleep Medicine and the American Academy of Dental Sleep Medicine. Dr Eli holds multiple patents in the fields of both sleep and pain.
Former NFL Superstars make Reservation at Mama Campisi’s Restaurant for Snoring Sleep Apnea Education and Screening ST. LOUIS, MO –Former NFL Superstars, Roy Green CARDINALS/EAGLES Wide Receiver, Eric Dickerson RAMS/COLTS/RAIDERS Running Back, Jackie Smith CARDINALS/COWBOYS Tight End, Isaiah Robertson, RAMS/BILLS Linebacker, Saturday December 12th from 11:00 am to 1:00 pm at Mama Campisi’s Restaurant to hear them explain that the rigors of a professional sports career often leave a lasting legacy of health issues which bear monitoring into retirement. “When a player’s athletic career ends, the level of exercise is reduced dramatically while caloric intake often remains high. This could lead to snoring and sleep apnea, along with other serious comorbidities,” said Andre Collins, Executive Director of the Professional Athletes Foundation and NFLPA Director of Former Players. “The HOPE Program provides former players with a team environment that encourages participants to adopt healthier lifestyle choices. David Gergen, President of the Pro Player Health Alliance (PPHA), knows that millions of people are not aware how poor sleep is affecting their health and overall well-being. “We all know what loud snoring is, but may not realize it can also be a symptom of sleep apnea”, said Gergen Bad sleep habits are also responsible for many serious health problems such as drowsy driving, memory problems, Type 2 Diabetes, depression, heart disease, moodiness and even erectile dysfunction. Former player, Larry Frost, wants all retired NFL Players in the St Louis area to take part in this free event and hear stories from former NFL players who have benefited from understanding more about their sleep health and why they are personally motivated to become so involved in educating the public. The event location is a landmark in Saint Louis: “Mama’s on the Hill” 2132 Edwards St Saint Louis, MO 314-776-3100 “Recently the news has been filled with sleep related deaths that can be linked directly to sleep apnea,” said Gergen. “These we know about because of their high public visibility but we know that there are thousands upon thousands of deaths that don’t make the news each year. The majority of these thousands of deaths are everyday people who walked through their dentist or primary care physicians doors unscreened and untested.” Also attending the event will be American Sleep and Breathing Academy health experts and dentists Bill Busch DDS, Jay Ohmes DDS and Kevin Postol DDS, who will be available to answer sleep health related questions and offer recommendations as to best practices and treatment. Sleep health screening using the Nox T3 by CareFusion home sleep diagnostic device and if indicated a ZQuiet anti-snoring mouthpiece will be provided at no charge as part of the screening. All data collected will be submitted to the Hope program for inclusion in the Living Heart Foundation sleep research program. ABOUT PRO PLAYER HEALTH ALLIANCE www.proplayersleep.org Pro Player Health Alliance (PPHA) is an organization dedicated to helping former NFL players, providing testing and treatment options for those who suffer from sleep apnea. Since launching in April 2012, over 260 players have been treated through PPHA’s “Tackle Sleep Apnea” campaign. The PPHA works closely with the American Sleep and Breathing Academy and is dedicated to improving health and wellness through sleep education and advocacy. ABOUT LIVING HEART FOUNDATION The Living Heart Foundation (LHF) is a nonprofit organization under IRS 501 (c) (3) code. The LHF was initially funded by a grant from the Edison Foundation. Subsequently, Funding sources and donations have been obtained from companies like Covidien, Pfizer, Meridian Health System, Siemens, Professional Athletes Foundation, and from individual sources. The LHF was established by Arthur J. Roberts, MD in April 2001 to combat sudden cardiac death and to provide cardiovascular risk stratification with early preventive intervention for cardiac, pulmonary, and metabolic conditions through on-site screening and integrated follow-up health programs. The LHF has published 10 peer review papers related to CV risk in college students & athletes, as well as former NFL athletes. ABOUT AMERICAN SLEEP AND BREATHING ACADEMY The ASBA provides networking opportunities with other members and organizations, lobbying for improved reimbursements while seeking to lower ever escalating health care provider costs, and discounts on educational events, products and accreditations for its members. This organization will help members more affordably lead the way to a new frontier in sleep medicine with the end goal to improve patient care through education for sleep professionals, sleep centers, patients and the community at large. Organizers of the American Sleep & Breathing Academy also founded the Sleep & Wellness Magazine and Sleep & Wellness Conference. Educational events for ASBA Members are funded in part by partnership with these organizations. Proceeds from those organizations and educational events are used towards the mission of the American Sleep & Breathing Academy, inc. and its members. ABOUT ZQUIET Sleeping Well, LLC (ZQuiet’s parent company) was founded in 2008 by a husband and wife seeking a solution for the chronic snoring problem that was literally ruining their marriage and impacting their health. They brought to market ZQuiet, an anti-snoring mouthpiece, that simplifies the treatment experience for sleep disordered breathing, and delivers an innovative, inexpensive and immediate treatment for snoring as a starting point for the professional continuum of care for all forms of sleep disordered breathing. ZQuiet offers a full suite of oral appliances to treat snoring and obstructive sleep apnea. Contacts Pro Player Health Alliance David Gergen 602-478-9713 gxployer@aol.com Living Heart Foundation Erich Sandoval – Lazar Partners 917-497-2867 esandoval@lazarpartners.com American Sleep and Breathing Academy Alan Hickey Alan@myasba.com ZQuiet Daniel Webster dan@zquiet.com SOURCE Pro Player Health Alliance Related Links www.proplayersleep.org Ahn Home Page www.zquiet.com